CELL PROLIFERATION KINETICS IN GOLDFISH ACCLIMATED TO VARIOUS TEMPERATURES
- 1 July 1972
- journal article
- Published by Wiley in Cell Proliferation
- Vol. 5 (4) , 331-339
- https://doi.org/10.1111/j.1365-2184.1972.tb00372.x
Abstract
Cell proliferation has been studied in goldfish which have been acclimated to temperatures of 6, 10, 15, 20, 30 and 37°C. Hemopoietic tissue and intestinal epithelium show similar temperature effects, but they are seen more clearly in the latter. The fraction of intestinal epithelial cells labeled by a single injection of tritiated thymidine decreases as the temperature increases above 20°C. The total tissue incorporation of DNA precursor also decreases with increasing temperature. On the other hand, the grain counts per nucleus tend to increase slightly with increasing temperature. The mean generation time as indicated by the rate of DNA turnover (loss of 125I‐DNA) shows little if any change as the temperature increases above 20°C. These observations imply that in the rapidly proliferating cells of the goldfish the mitotic cycle is remarkably insensitive to temperature change, except for the DNA synthesis phase, which has a temperature dependence (Q10= 2.6) characteristic of enzyme‐mediated chemical reactions.Keywords
This publication has 17 references indexed in Scilit:
- The effect of acclimation temperature on amino acid transport in the goldfish intestineComparative Biochemistry and Physiology Part A: Physiology, 1971
- The effect of thermal acclimation upon brain acetylcholinesterase activity of andLife Sciences, 1969
- Choline acetyltransferase activity in the brain of goldfish acclimated to different temperaturesComparative Biochemistry and Physiology, 1969
- Changes in activity of cytochrome oxidase during adaptation of goldfish to different temperaturesComparative Biochemistry and Physiology, 1965
- Cell Population Studies on the Intestine of Continuously Irradiated RatsRadiation Research, 1963
- Some Problems Associated with the Histological Study of Cell Proliferation KineticsCYTOLOGIA, 1961
- Physiological and biochemical adaptation of goldfish to cold and warm temperatures. II. Oxygen consumption of liver homogenate; oxygen consumption and oxidative phosphorylation of liver mitochondriaJournal of Cellular and Comparative Physiology, 1959
- Physiological and biochemical adaptation of goldfish to cold and warm temperatures. I. Standard and active oxygen consumptions of cold‐ and warm‐acclimated goldfish at various temperaturesJournal of Cellular and Comparative Physiology, 1959
- OXYGEN CONSUMPTION, BRAIN METABOLISM AND RESPIRATORY MOVEMENTS OF GOLDFISH DURING TEMPERATURE ACCLIMATIZATION, WITH SPECIAL REFERENCE TO LOWERED TEMPERATURESThe Biological Bulletin, 1950
- Cruising Speed of Goldfish in Relation to Water TemperatureJournal of the Fisheries Research Board of Canada, 1948