Synthesis of a key intermediate for preparation of 4,5-didehydro prostaglandins containing an allenyl side-chain group via two-component coupling process. Synthesis of enprostil
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 10,p. 1251-1252
- https://doi.org/10.1039/c39940001251
Abstract
Enone 8, a key intermediate in the preparation of 4,5-didehydro prostaglandins via a two component coupling process, is prepared efficiently from readily available enone 6; the synthesis of enprostil, an antiulcer agent developed by Syntex, using enone 8 is also described.Keywords
This publication has 0 references indexed in Scilit: