Death and blindness due to overdose of quinine.
- 6 July 1985
- Vol. 291 (6487) , 31-33
- https://doi.org/10.1136/bmj.291.6487.31
Abstract
During 1953-83 there were 48 admissions to the regional poisoning treatment centre, Edinburgh, for overdose of quinine including 19 since 1978. Six patients were blind and one had ventricular tachycardia. Stellate ganglion block was performed without benefit in seven patients. No patient died, but three deaths from cardiotoxicity occurred in a further 71 patients reported to the Scottish Poisons Information Bureau. Plasma quinine concentration related to time from ingestion was found to be a useful predictor of visual toxicity.Keywords
This publication has 16 references indexed in Scilit:
- COMPLICATIONS OF QUININE POISONINGThe Lancet, 1985
- Loss of sight after self poisoning with quinine.BMJ, 1983
- Optics of photorefraction: orthogonal and isotropic methodsJournal of the Optical Society of America, 1983
- Quinine overdose Prevention of visual damage by stellate ganglion blockAnaesthesia, 1983
- Ocular Quinine ToxicityAmerican Journal of Ophthalmology, 1980
- Convulsions during Stellate Ganglion BlockAnesthesia & Analgesia, 1979
- Determination of Quinidine and its major metabolites by high-performance liquid chromatographyJournal of Chromatography B: Biomedical Sciences and Applications, 1979
- Electroretinogram Changes in Acute Quinine PoisoningArchives of Ophthalmology (1950), 1973
- QUININE AMBLYOPIAActa Ophthalmologica, 1955
- VENTRICULAR TACHYCARDIA AND BILATERAL AMAUROSIS PRODUCED BY QUININE POISONINGArchives of internal medicine (1960), 1947