A Case Report of "Cape Cod" Rocky Mountain Spotted Fever with Multiple Coagulation Disturbances

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Abstract
A case of "Cape Cod" Rocky Mountain Spotted Fever complicated by thrombocytopenia, circulating anticoagulant activity, and deficiency of Vitamin K-dependent clotting factors that responded to the intravenous administration of Vitamin K has been presented. To our knowledge, this is the first such case described. Coagulation studies supported, in part, by grants from the Wimpfheimer Foundation and the John A. Hartford Foundation. We are indebted to Dr. Sherwin V. Kevy of the Children's Hospital Medical Center for performing tests of fibrinolysis and to Dr. Edward S. Murray of the Department of Microbiology of the Harvard School of Public Health for his assistance in the isolation of Rickettsia and the performance of the serologic tests for diagnosis.

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