Penetration of Metronidazole and Tinidazole into the Aqueous Humor in Man
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in Chemotherapy
- Vol. 29 (3) , 188-191
- https://doi.org/10.1159/000238196
Abstract
Metronidazole or tinidazole (500 mg) were given as a 20 min infusion each to 10 patients who were hospitalized for elective cataract extraction. Metronidazole and tinidazole concentrations in aqueous humor were 5.2 .+-. (SE) 0.5 and 5.3 .+-. 0.7 .mu.g/ml, respectively, 20-70 min after the end of the infusion. Aqueous humor/serum concentration ratios were 0.38 and 0.47 on the average for metronidazole and tinidazole, respectively.This publication has 0 references indexed in Scilit: