Variations in affect following amphetamine and placebo: Markers of stimulant drug preference.
- 1 January 2003
- journal article
- clinical trial
- Published by American Psychological Association (APA) in Experimental and Clinical Psychopharmacology
- Vol. 11 (1) , 91-101
- https://doi.org/10.1037//1064-1297.11.1.91
Abstract
Variations in affect following d-amphetamine and placebo were examined in healthy young adults who subsequently preferred d-amphetamine (choosers; n = 61) or placebo (nonchoosers; n = 48) in a drug preference procedure. Affect was assessed before and 1, 3, and 6 hr after participants received the placebo and 10 mg d-amphetamine. Following amphetamine as compared with placebo, choosers' ratings increased on scales measuring energy, cognitive efficiency, and well-being, and decreased on scales measuring fatigue and sedation. Nonchoosers reported no effects, sedative effects, and dysphoric effects of amphetamine. Following placebo, ratings of energy, efficiency, and well-being decreased, and ratings of sedation increased in choosers but not in nonchoosers. Variations in affect following placebo and amphetamine may constitute markers of risk for drug use.Keywords
This publication has 0 references indexed in Scilit: