Myelograms Relating to Anemia and Hematopoiesis Following Thermal Injury in Rats.
- 1 March 1957
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 94 (3) , 489-493
- https://doi.org/10.3181/00379727-94-22988
Abstract
Marrow weights and the numbers of cells per mm3 in femoral marrow of erythrocytes, total leukocytes, immature and mature neutrophilic granulocytes were obtained in uninjured rats, bled rats, and rats given thermal injuries in water at 90cC for 35 seconds of 20% and 50% body surface. Significantly lower numbers of erythrocytes, total leukocytes and neutrophilic granulocytes were found in the thermally injured rats during first two weeks following injury. The numbers of these cells were inversely related to the percentage of body surface injured. These data support the conclusion that medullary hematopoiesis is suppressed after thermal injury and this suppression is partially responsible for the circulatory anemia found in thermally injured animals.Keywords
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