Structure and Assembly of the Native Collagen Fibril
- 1 January 1982
- journal article
- Published by Taylor & Francis in Connective Tissue Research
- Vol. 10 (1) , 25-36
- https://doi.org/10.3109/03008208209034403
Abstract
Assembly in vitro of the native collagen fibril is a multistep process involving an initial intermediate of unknown structure, linear growth of thin filaments, lateral growth to form the fibril, and stabilization by covalent crosslinks. A model for the structure of the fibril is proposed consisting of a substructure of five-stranded microfibrils laterally compressed to place molecules in cross section on a near-hexagonal lattice.Keywords
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