Abstract
In a report appearing in 1951, Southam et al1 reported on the natural history of 173 patients with acute leukemia treated supportively at Memorial Center for Cancer and Allied Diseases in New York City from 1926 to 1948. The study population included 65 children less than 10 years of age. The average length of survival of these patients was 19.3 weeks after the onset of symptoms attributable to leukemia. Of the entire sample of patients irrespective of age, only 4 (2.3%) survived 52 weeks or beyond.

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