The Docking of Arg2 of Angiotensin II with Asp281 of AT1 Receptor Is Essential for Full Agonism
Open Access
- 1 May 1995
- journal article
- Published by Elsevier
- Vol. 270 (21) , 12846-12850
- https://doi.org/10.1074/jbc.270.21.12846
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Non-peptide Angiotensin Agonist: FUNCTIONAL AND MOLECULAR INTERACTION WITH THE AT1 RECEPTORPublished by Elsevier ,1995
- Structural model of antagonist and agonist binding to the angiotensin II, AT1 subtype, G protein coupled receptorChemistry & Biology, 1994
- STRUCTURE AND FUNCTION OF G PROTEIN-COUPLED RECEPTORSAnnual Review of Biochemistry, 1994
- A structural role for arginine in proteins: Multiple hydrogen bonds to backbone carbonyl oxygensProtein Science, 1994
- Mutation of Asp74 of the rat angiotensin II receptor confers changes in antagonist affinities and abolishes G-protein coupling.Proceedings of the National Academy of Sciences, 1993
- Identification of amino acid residues of rat angiotensin II receptor for ligand binding by site directed mutagenesisBiochemical and Biophysical Research Communications, 1992
- Isolation of a cDNA encoding the vascular type-1 angiotensin II receptorNature, 1991
- Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptorNature, 1991
- Hydrogen bonding and biological specificity analysed by protein engineeringNature, 1985
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973