Hemorrhage from Duodenal Ulcer during the Administration of Reserpine

20 December 1956

journal article
Published by Massachusetts Medical Society in New England Journal of Medicine

Vol. 255 (25) , 1193-1194
https://doi.org/10.1056/nejm195612202552506

Abstract

RESERPINE has become increasingly popular in a wide variety of clinical conditions since its isolation in 1952.¹ The hypotensive and bradycardic action is useful in the treatment of hypertension.² The tranquilizing effect is valuable in neuropsychiatric disorders.³ ⁴ ⁵ With the larger dosages now being used and the longer clinical experience with reserpine, several serious side effects have been noted. Recent studies have paid particular attention to the gastrointestinal tract.In dogs, stimulation of gastric hydrochloric acid production by reserpine in both the vagally innervated gastric fistula pouch and the vagally denervated Heidenhain pouch has been demonstrated by Barrett et al.⁶ These . . .

Keywords

This publication has 7 references indexed in Scilit:

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