Psoriatic therapeutics and glucose-6-phosphate dehydrogenase
- 1 January 1975
- journal article
- research article
- Published by Springer Nature in Archives of Dermatological Research
- Vol. 252 (2) , 147-149
- https://doi.org/10.1007/bf00561837
Abstract
Summary The inhibitory effects of various agents on the enzyme glucose-6-phosphate dehydrogenase have been studied in vitro. Stress is laid on the calculation of kinetic parameters such as trueK I values. The most active inhibitor was methotrexate, closely followed by cGMP. The increase in inhibitory activity after incubation of methotrexate with liver slices is discussed.Keywords
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