Unbinding transitions and phase separation of multicomponent membranes
- 1 July 2000
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review E
- Vol. 62 (1) , R45-R48
- https://doi.org/10.1103/physreve.62.r45
Abstract
Multicomponent membranes in contact with another surface or wall are studied by a variety of theoretical methods and Monte Carlo simulations. The membranes contain adhesion molecules which are attracted to the wall and, thus, act as local stickers. It is shown that this system undergoes lateral phase separation leading to discontinuous unbinding transitions if the adhesion molecules are larger than the nonadhesive membrane components. This process is driven by an effective line tension which depends on the size of the stickers and arises from the interplay of shape fluctuations and sticker clusters.Keywords
This publication has 15 references indexed in Scilit:
- Stripe Phases in Lipid Monolayers near a Miscibility Critical PointPhysical Review Letters, 1999
- Flexible membranes with anchored polymersColloids and Surfaces A: Physicochemical and Engineering Aspects, 1997
- Adhesion-induced domain formation by interplay of long-range repulsion and short-range attraction force: a model membrane studyBiophysical Journal, 1997
- Electrostatic adhesion between fluid membranes: phase separation and blisteringEurophysics Letters, 1997
- Adhesion of Membranes via Anchored StickersPhysical Review Letters, 1996
- The morphology of lipid membranesCurrent Opinion in Structural Biology, 1995
- Detection of phase separation in fluid phosphatidylserine/phosphatidylcholine mixturesBiophysical Journal, 1994
- Phosphatidylcholine: cholesterol phase diagramsBiophysical Journal, 1992
- Lateral diffusion in the liquid phases of dimyristoylphosphatidylcholine/cholesterol lipid bilayers: a free volume analysisBiochemistry, 1992
- Phase separations in phospholipid membranesBiochemistry, 1975