METABOLISM IN MYOTONIA ATROPHICA
- 1 October 1931
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 48 (4) , 569-575
- https://doi.org/10.1001/archinte.1931.00150040035002
Abstract
Myotonia atrophica or dystrophica is one of the rarer forms of myopathy, which, in addition to the typical myotonia, is characterized by the following conditions: (1) onset usually in the third decade; (2) limitation of the myotonia to special groups of muscles, namely, those of the hands, the tongue and the legs; (3) typical distribution of the atrophy to the face, the sternocleidomastoid muscles, the hand and the forearm and the muscles of the leg; (4) general emaciation; (5) baldness; (6) testicular atrophy; (7) cataract; (8) defect in speech; (9) combination with ataxia and Westphal's sign.1 The etiology of this disease is obscure. Naegeli2 regarded the pathogenesis of the disease as originating in a polyglandular disturbance, presumably with a marked hereditary predisposition. This relation to endocrine involvement was also assumed by Barkman3 and others, though the evidence for this is more circumstantial than direct. The occurrence ofThis publication has 0 references indexed in Scilit: