Increased Metallothionein Content in Rat Liver Induced by X Irradiation and Exposure to High Oxygen Tension
- 1 August 1983
- journal article
- research article
- Published by JSTOR in Radiation Research
- Vol. 95 (2) , 298-302
- https://doi.org/10.2307/3576256
Abstract
X irradiation and exposure to high O2 tension are known to induce lipid peroxidation. The effects of these stresses on hepatic content of metallothionein, which may be involved in the regulation of Zn and Cu metabolism, were studied. The amount of metallothionein in rat liver was increased 11-fold by a high dose of X irradiation (1000 R). Increased metallothionein content (about 15 times) was also observed in liver of rats exposed to high O2 tension for 3 days.This publication has 3 references indexed in Scilit:
- Increase in hepatic metallothionein in rats treated with alkylating agentsToxicology and Applied Pharmacology, 1979
- Protection of carbon tetrachloride-induced hepatotoxicity by zinc: Role of metallothioneinToxicology and Applied Pharmacology, 1979
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951