Long-term results of medical therapies for benign prostatic hyperplasia

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Abstract
Symptoms of benign prostatic hyperplasia are present in the majority of men aged 60 years and older. The Benign Prostatic Hyperplasia Guidelines recommend medical treatment with finasteride or α-blockers and watchful waiting as treatment options for men with bothersome symptoms. Finasteride therapy reduces the volume of the hyperplastic prostate gland, improves the symptoms associated with bladder outlet obstruction, and halts the inevitable progression of the disease. Terazosin, a selective long acting α1-blocker, reduces bladder outlet obstruction via prostatic smooth muscle relaxation and thus improves urinary flow and symptoms in men with benign prostatic hyperplasia.

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