Primordial germ-cell development: the zebrafish perspective

1 September 2003

journal article
research article
Published by Springer Nature in Nature Reviews Genetics

Vol. 4 (9) , 690-700
https://doi.org/10.1038/nrg1154

Abstract

Primordial germ cells follow a characteristic developmental path that is manifested in the specialized regulation of basic cell functions and behaviour. Recent studies in zebrafish have greatly enhanced our understanding of the mode of specification of primordial germ cells, cell-fate maintenance and the migration of these cells towards their target, the gonad, where they differentiate into gametes.

Keywords

This publication has 103 references indexed in Scilit:

The art and design of genetic screens: zebrafish
Nature Reviews Genetics, 2001
Vasa Homolog Genes in Mammalian Germ Cell Development.
Cell Structure and Function, 2001
Effective targeted gene ‘knockdown’ in zebrafish
Nature Genetics, 2000
Signaling for germ cells
Genes & Development, 1999
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
Nature, 1998
Vertebrate genome evolution and the zebrafish gene map
Nature Genetics, 1998
The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood
The Journal of Experimental Medicine, 1997
Translational regulation of nanos by RNA localization
Nature, 1994
Genetics and early development of zebrafish
Trends in Genetics, 1989
Contact relations and guidance of primordial germ cells on their migratory route in embryos ofXenopus laevis
Proceedings of the Royal Society of London. B. Biological Sciences, 1981