Differential DNA damage in response to the neonatal and adult excitotoxic hippocampal lesion in rats
- 1 December 2000
- journal article
- research article
- Published by Wiley in European Journal of Neuroscience
- Vol. 12 (12) , 4424-4433
- https://doi.org/10.1046/j.0953-816x.2000.01320.x
Abstract
We examined the developmental profile of excitotoxin‐induced nuclear DNA fragmentation using the transferase dUTP nick‐end labelling (TUNEL) technique, as a marker of DNA damage and cell death in rat...Keywords
This publication has 42 references indexed in Scilit:
- Disruption of Latent Inhibition in Rats with Postnatal Hippocampal LesionsNeuropsychopharmacology, 1999
- DNA Fragmentation and Prolonged Expression of c-fos, c-jun, and hsp70 in Kainic Acid-Induced Neuronal Cell Death in Transgenic Mice Overexpressing Human CuZn-Superoxide DismutaseJournal of Cerebral Blood Flow & Metabolism, 1997
- Apoptosis and Necrosis after Reversible Focal Ischemia: An in Situ DNA Fragmentation AnalysisJournal of Cerebral Blood Flow & Metabolism, 1996
- Naturally occurring cell death in the developing cerebral cortex of the rat. Evidence of apoptosis-associated internucleosomal DNA fragmentationNeuroscience Letters, 1994
- Regulation of N-methyl-d-aspartate (NMDA) receptor function during the rearrangement of developing neuronal connectionsPublished by Elsevier ,1994
- Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.The Journal of cell biology, 1992
- Sparing of function after neonatal frontal lesions correlates with increased cortical dendritic branching: a possible mechanism for the Kennard effectBehavioural Brain Research, 1991
- Rapid transneuronal degeneration and death of cortical neurons following removal of the olfactory bulb in adult ratsJournal of Comparative Neurology, 1978
- Functional development of the prefrontal cortex in early life and the problem of neuronal plasticityExperimental Neurology, 1971
- CORTICAL REORGANIZATION OF MOTOR FUNCTIONArchives of Neurology & Psychiatry, 1942