Metabolism of ornithine, α-ketoglutarate and arginine in isolated perfused rat liver

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Abstract
Ornithine (Orn; KG) salt) and arginine (Arg) supplementation of enteral diets has been advocated in the treatment of hypercatabolism of trauma patients, but both compounds are subject to extensive hepatic metabolism. To compare the metabolism of these two compounds and to evaluate the possible influence of the KG, Orn, ornithine . 178 (SD 30) nmol/min per g liver), and Orn uptake was not modified by 44 (SD 0. Orn 0ol/min per g liver). KG metabolic interaction, mostly in proiine metabolism, which occurs in the splanchnic area.