Novel Antiinflammatory Vascular Benefits of Systemic and Stent-Based Delivery of Ethylisopropylamiloride
- 14 December 2004
- journal article
- Published by Wolters Kluwer Health in Circulation
- Vol. 110 (24) , 3721-3726
- https://doi.org/10.1161/01.cir.0000146790.51331.ba
Abstract
Background— Recently, we demonstrated that the amiloride derivative ethylisopropylamiloride (EIPA) limits vascular smooth muscle cell growth and migration. The purpose of the present experiments was to determine whether EIPA can also reduce the inflammatory component of atherogenesis and stent neointima formation.Keywords
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