Method for the synthesis of 4-substituted acetoacetates
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 24,p. 932-933
- https://doi.org/10.1039/c39770000932
Abstract
Ethyl 4-bromo-3-oxobutyrate can be converted with sodium hydride into the enolate salt and nucleophilic substitutions can thereafter be carried out at the 4-carbon atom.Keywords
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