Mammalian Metallothionein Is Functional in Yeast
- 21 February 1986
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 231 (4740) , 854-856
- https://doi.org/10.1126/science.3080806
Abstract
Expression of two monkey metallothioneins in yeast leads to complementation of both known functions of the endogenous yeast copperthionein gene, namely copper detoxification and autoregulation of transcription. The metallothionein-like proteins of higher and lower eukaryotes are therefore functionally analogous despite their dissimilar primary sequences.This publication has 10 references indexed in Scilit:
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