Studies of the coding region of the neuronal glutamate transporter gene in amyotrophic lateral sclerosis
- 1 June 1995
- journal article
- Published by Wiley in Annals of Neurology
- Vol. 37 (6) , 817-819
- https://doi.org/10.1002/ana.410370618
Abstract
Studies of the coding region of the neuronal glutamate transporter of 6 amyotrophic lateral sclerosis (ALS) patients and 10 controls show an identical pattern of four reported amino acid variations. No mutations and polymorphisms were detected in 5 sporadic ALS patients and a single patient with the familial form of the disease.Keywords
This publication has 13 references indexed in Scilit:
- Neuron-specific human glutamate transporter: molecular cloning, characterization and expression in human brainBrain Research, 1994
- Localization of neuronal and glial glutamate transportersNeuron, 1994
- Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity.Proceedings of the National Academy of Sciences, 1993
- Synaptosomal Glutamate Uptake Declines Progressively in the Spinal Cord of a Mutant Mouse with Motor Neuron DiseaseJournal of Neurochemistry, 1993
- Cloning and expression of a rat brain L-glutamate transporterNature, 1992
- Primary structure and functional characterization of a high-affinity glutamate transporterNature, 1992
- Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.Proceedings of the National Academy of Sciences, 1992
- Decreased Glutamate Transport by the Brain and Spinal Cord in Amyotrophic Lateral SclerosisNew England Journal of Medicine, 1992
- Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.Proceedings of the National Academy of Sciences, 1989
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences, 1977