Butorphanol Does Not Reduce the Minimum Alveolar Concentration of Halothane in Dogs
- 1 March 1994
- journal article
- Published by Wiley in Veterinary Surgery
- Vol. 23 (2) , 156-159
- https://doi.org/10.1111/j.1532-950x.1994.tb00462.x
Abstract
This study evaluated the effect of butorphanol tartrate, a synthetic opioid agonist-antagonist, on halothane minimum alveolar concentration (MAC) in dogs. Baseline halothane MAC was determined in each of six dogs. Butorphanol was administered and halothane MAC was redeter-mined. Each dog received butorphanol at 0.2, 0.4, and 0.8 mg/kg intravenously at 1 week intervals. Heart rate and arterial blood pressure decreased after butorphanol administration, but returned to baseline by 50 minutes. There was little effect on respiratory parameters. A halothane-sparing effect was not noted with any butorphanol dose.Keywords
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