Chronic Pulmonary Coccidioidomycosis

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Abstract
Of 109 patients with proved coccidioidomycosis 20 had chest films and clinical findings indistinguishable from either chronic pulmonary histoplasmosis or chronic pulmonary tuberculosis. Many were thought to have tuberculosis for years before the fungal etiology of the lung disease was determined. Coccidioides immitis was cultured from sputums of 18 of 19 patients, and coccidioidin complement-fixation tests were positive in 14 of 15. Best therapeutic results were obtained with amphotericin B intravenously in a total dose of 30 mg per kilogram of body weight or more.