Clonal Origin of Inherited Medullary Thyroid Carcinoma and Pheochromocytoma
- 23 July 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 193 (4250) , 321-323
- https://doi.org/10.1126/science.935869
Abstract
A black female with inherited medullary thyroid carcinoma and pheochromocytoma was a mosaic for glucose-6-phosphate dehydrogenase types A and B in normal tissues (blood, thyroid, and adrenal gland); both the medullary carcinoma and pheochromocytoma tissue showed a B pattern only. This finding suggests a single clone origin for each of the tumors. Other inherited tumors similarly studied in man have appeared to be multiclonal in origin.This publication has 20 references indexed in Scilit:
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