An HPLC Method for Measuring 5-Fluorouracil in Plasma
- 1 June 1984
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 7 (7) , 1489-1494
- https://doi.org/10.1080/01483918408074060
Abstract
5-Fluorouracil in plasma was determined by extraction with methyl isobutyl ketone, evaporation of the ketone, and reverse phase high performance liquid chromatography of the evaporation residue. With UV detection at 280 nm the lower limit of detection is 10.0 ng/ml and interfering peaks eliminated. The method is highly reproducible.This publication has 7 references indexed in Scilit:
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