Incomplete anaerobiosis as a cause of metronidazole 'resistance'.
Open Access
- 1 October 1978
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 31 (10) , 933-935
- https://doi.org/10.1136/jcp.31.10.933
Abstract
Clostridium welchii, used as a control, was found to grow well in a microaerophilic jar used for campylobacters but appeared resistant to a metronidazole disc although the campylobacter was sensitive. Minimum inhibitory concentrations for six strains of Cl. welchii were up to 64-fold higher in these conditions than when grown anaerobically. Zones of inhibition with both Cl. welchii and Bacteroides fragilis varied with the amount of air admitted to anaerobic jars.This publication has 1 reference indexed in Scilit:
- Light inactivation of metronidazole sensitivity discs.Journal of Clinical Pathology, 1977