Long-standing asymptomatic primary sclerosing cholangitis report of three cases
- 1 September 1981
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 26 (9) , 778-782
- https://doi.org/10.1007/bf01309608
Abstract
Three patients, two males and one female, with asymptomatic primary sclerosing cholangitis (PSC) are described. The diagnosis was made in each case by endoscopic retrograde cholangiography after investigation of persistent elevation of the serum alkaline phosphatase. All three have remained completely well without any medical or surgical treatment for 3, 7, and 15 years, respectively, despite extensive involvement of the biliary tree. Follow-up liver biopsies in two have shown no histological evidence of progression to secondary biliary cirrhosis. PSC may occur more frequently and may follow a less severe clinical course than previously recognized.This publication has 13 references indexed in Scilit:
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