Asymmetric Allylboration of Aldehydes and Ketones Using 3,3‘-Disubstitutedbinaphthol-Modified Boronates
- 16 July 2004
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 6 (16) , 2701-2704
- https://doi.org/10.1021/ol0490882
Abstract
Allylboronates derived from 3,3‘-disubstituted 2,2‘-binaphthols react with aldehydes and ketones to give the expected allylated products with up to >99:1 er. Highest selectivities were observed for aromatic ketones. The bis(trifluoromethyl) derivative is particularly outstanding in terms of reactivity, selectivity, and robustness.Keywords
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