Sedimentation Behavior of Desoxypentose Nucleic Acids from Normal and Pathologic Human Spleens

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Abstract
Sedimentation curves of DNA from spleens of normal individuals and patients with diseases causing a leukocyte infiltration in the spleen were obtained by means of the ultracentrifuge. DNA was dissolved in cacodylate buffer (pH 7; u 0.3) at concentrations range 1-20 mg % of P DNA. No differences in sedimentation curves of DNA from normal and infiltrated splens were noted.