Comparative study of immunologic methods for demonstration of antibodies to soluble nuclear antigens
- 1 March 1977
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 20 (2) , 693-701
- https://doi.org/10.1002/art.1780200209
Abstract
Four methods to detect antibodies reactive with soluble nuclear antigens were compared—the fluorescent antibody technique, hemagglutination, complement fixation, and immunodiffusion. Certain advantages and disadvantages of each method are described. The first three methods have greater sensitivity than immunodiffusion, but immunodiffusion discriminates most reliably between different antibodies.This publication has 20 references indexed in Scilit:
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