Syringomesencephalia

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Abstract
A woman had progressive neurologic deterioration attributed to multiple sclerosis. Ophthalmologic findings were consistent with a unilateral lesion of the medial longitudinal fasciculus. Autopsy disclosed a mesencephalic syrinx and cerebellar atrophy secondary to alcoholism. Syringomesencephalia is distinctly uncommon; this is the third known case to our knowledge.