GOLGI COMPLEX ALTERATIONS INDUCED BY X537A IN CHIEF CELLS OF RAT PARATHYROID-GLAND

  • 1 January 1976
    • journal article
    • research article
    • Vol. 35  (5) , 425-429
Abstract
EM examination of chief cells of rat parathyroid glands incubated with the antibiotic ionophore X537A showed selective alterations of the Golgi complex. The changes were dependent on the duration of X537A exposure. After 60 min of incubation, the cisternae and vesicles of the Golgi complex appeared highly swollen and disorganized. Because of its selective action, X537A might be a useful tool in the investigation of the role of Golgi apparatus in parathormone secretion.