Growth Mechanisms in Skulls with Facial CleftsDescriptive and Experimental Studies on the Facial Skeleton

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Abstract
During postnatal growth, skulls of patients with untreated unilateral clefts of the alveolus and palate develop additional anomalies of the facial skeleton. Similar anomalies a deviation of the upper jaw to the non-cleft side and a retropositioning of the maxilla on the cleft side develop in rabbits with the same type of cleft, surgically produced in the fourth week after birth. Based on a quantitative study of the postnatal growth of the rabbit skull under normal and various experimental conditions, a mechanisms is proposed for the late development of anomalies of the facial skeleton in cleft-affected skulls.

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