CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
- 4 June 2007
- journal article
- Published by Elsevier
- Vol. 359 (3) , 716-722
- https://doi.org/10.1016/j.bbrc.2007.05.182
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: Potential regulation by ligand-dependent degradation and HIF-1αBiochemical and Biophysical Research Communications, 2006
- Sp1 Is Involved in Akt-mediated Induction of VEGF Expression through an HIF-1–independent MechanismMolecular Biology of the Cell, 2004
- Simultaneously Targeting Epidermal Growth Factor Receptor Tyrosine Kinase and Cyclooxygenase-2, an Efficient Approach to Inhibition of Squamous Cell Carcinoma of the Head and NeckClinical Cancer Research, 2004
- Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasisThe FASEB Journal, 2004
- Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancerNature Reviews Drug Discovery, 2004
- Hypoxia-Inducible Factor-1 Mediates Activation of Cultured Vascular Endothelial Cells by Inducing Multiple Angiogenic FactorsCirculation Research, 2003
- Tumorigenesis and the angiogenic switchNature Reviews Cancer, 2003
- VEGF and the quest for tumour angiogenesis factorsNature Reviews Cancer, 2002
- Endothelin-1 Induces Vascular Endothelial Growth Factor by Increasing Hypoxia-inducible Factor-1α in Ovarian Carcinoma CellsJournal of Biological Chemistry, 2002
- The mRNA Expression of Cyclo-oxygenase-2 (COX-2) and Vascular Endothelial Growth Factor (VEGF) in Human Breast CancerCurrent Medical Research and Opinion, 2002