Sick Chaperones, Cellular Stress, and Disease
Top Cited Papers
- 6 October 2005
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 353 (14) , 1489-1501
- https://doi.org/10.1056/nejmra050111
Abstract
This review discusses the structure and function of molecular chaperones, with emphasis on their role in rescuing misfolded proteins. It also includes a discussion of the diseases in which abnormalities of these caretaker molecules or their molecular partners have been found.Keywords
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