Diethylnitrosamine-Induced Alterations in the Tracheobronchial System of Syrian Golden Hamsters2
- 1 May 1971
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 46 (5) , 1067-1071
- https://doi.org/10.1093/jnci/46.5.1067
Abstract
Diethylnitrosamine-induced alterations in the tracheobronchial system of Syrian golden hamsters were studied with semithin techniques. Hyperplasia and dysplasia of the epithelium seemed to precede papillary tumor development. These morphological patterns were repeated in the tumor epithelium. No evidence was found for metaplastic change to squamous epithelium either in the altered tracheobronchial or tumor epithelium.Keywords
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