Effect of Reduced Tissue Pressure on Blood Flow of the Fingers; the Veni-Vasomotor Reflex

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Abstract
The effect of reduced tissue pressure, down to -100 mm. Hg, on the blood flow of the finger was measured by the venus- occlusion plethysmograph in 5 normal subjects. Reduction of tissue pressure markedly decreases the blood flow, to 50% at -40 mm. Hg and to 10% at -100 mm. Hg. This is interpreted as additional evidence of a "veni-vasomotor reflex," by which distention of the venous vessels elicits a constriction in the arterioles. Since previous work with positive tissue pressures had also shown a decrease in flow, this is at a max. at the normal tissue pressure.