Predominant expression of σ and ε globin genes in human leukemia K-562(S6) variant cell line
- 1 April 1983
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 39 (4) , 415-416
- https://doi.org/10.1007/bf01963156
Abstract
In the human leukemia K-562(S6) cell line (a) the accumulation ofa-globin chains is low or absent, (b) ζ-globin gene expression is correlated with expression of ε-chains and (c) the genes responsible for the terminal cell division are not operated within 8–12 cell cycles, while K-562 (S6) cells are fully induced to erythroid differentiation.Keywords
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