Effect of random airway sizes on aerosol deposition

Abstract
A previously developed deposition model is used to determine the total and regional deposition of inhaled aerosols in a population of human lungs by taking into account variability in airway dimensions. The results for particle sizes ranging from 0.1 µm to 8 µm aerodynamic diameter agree favorably with experimental data, thus suggesting that observed intersubject deposition variability is caused pirimarily by difference in airway dimensions.

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