In Vivo Effect of Progesteron and Estrogen on Thymus Mass and T-Cell Functions in Female Mice
- 1 April 1984
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 16 (04) , 201-203
- https://doi.org/10.1055/s-2007-1014742
Abstract
Progesteron and estradiol, administered in doses equivalent to those used for therapy caused a marked transient reduction of the thymus mass, but did not affect the cellularity of other lymphoid organs. Humoral and cellular immune response of the hormone-treated mice was normal at the time of thymus involution. The same was true for the stem-cell differentiation capacity. The remaining thymus cells after hormone treatment showed increased DNA-synthesis.Keywords
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