Missing Y chromosome in juvenile chronic myelogenous leukemia
- 1 January 1975
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 29 (3) , 259-264
- https://doi.org/10.1007/bf00297633
Abstract
A child with Ph1-negative juvenile chronic myelogenous leukemia (CML) is presented. The only chromosomal abnormality in hematopoietic tissues consisted of an absent Y chromosome. While a missing Y chromosome in adult patients with CML may be associated with a better prognosis, the clinical course in our patient was as malignant as that usually observed in other children with Ph1-negative juvenile CML. This publication is No. 626 from the Department of Biophysics and Genetics, University of Colorado Medical Center.This publication has 16 references indexed in Scilit:
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