Ca exchange in isolated turtle ventricle

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Abstract
Ca content and Ca exchange (studied by means of the isotope Ca45) have been determined in vitro in turtle ventricles and frog skeletal muscles. The Ca exchangeability has been found much greater in cardiac than in skeletal muscles. Stretching further increases the cardiac Ca exchange and the hypodynamic state decreases it. Stimulation at a maximal rate of 24/min. has little effect in out experimental conditions and changes in total Ca content are small. It is suggested that the greater exchangeability of the Ca of cardiac as compared to skeletal muscle may explain the fact that cardiac is more sensitive than skeletal muscle to changes in the Ca concentration of the medium.

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