Diurnal rhythm of lipofuscin pigment in neurocytes of certain nuclei of mouse hypothalamus∗

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Abstract
In sexually mature male and female mice the percentage of neurocytes containing lipofuscin pigment (LFP) has been specified as well as the accumulation of this pigment in the para‐ventricular nucleus (PVN), the arcuate nucleus (AN), and the supraoptic nucleus (SON). It has been found that the number of neurocytes containing LFP as well as the accumulation of LFP in PVN, AN and SON show essential diurnal changes. The greatest number of neurocytes containing LFP and also the concentration of this pigment in PVN, AN and SON were observed at 18.00 h, both in males and in females, and the smallest number at 6.00 h.