Preparation of Microspheres of Poly(Glycidyl Methacrylate) and its Derivatives as Carriers for Immobilized Proteins

Abstract
Microspheres of poly(glycidyl methacrylate) and its derivatives were prepared. The diameter varied from 0.5-5 .mu.m. Proteins were immobilized on the microspheres by various processes. The maximum amount of covalently immobilized .gamma.-globulin on the microspheres was .apprx. 6 mg/m2. Dyed microspheres with a diameter of 2-4 .mu.m were applicable to immunological agglutination tests on a microplate as carrier particles substituting for red blood cells.