Gradient reversal technique and its applications to chemical-shift-related NMR imaging

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Abstract
The chemical‐shift effect often degrades slice selectivity thereby degrading the contrast and spatial resolutions in a high‐field NMR imaging. We propose a new pulse sequence which can compensate for this chemical‐shift effect during slice selection. This technique provides correct slice definition as well as clear separation between water and lipid protons in high‐field proton NMR imaging. Particular applications of this technique are 2D imaging with a thin‐slice selection and chunk 3D imaging, where correction of the chemical‐shift effect in slice selection is important. Another interesting application of the technique is chemical‐shift‐selective (CHESS) imaging. This technique does not require spectral‐selective rf pulses and it takes advantage of the chemical‐shift effect during slice selection. The latter is found to be useful for human in vivo chemical‐shift imaging in high‐field NMR. In this paper, the theoretical derivation of the proposed gradient reversal technique, its applications, and related experimental results are presented. © 1987 Academic Press, Inc.

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