Regions containing repeating base-pairs in DNA from some oncogenic and nononcogenic animal viruses.
- 1 June 1967
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 57 (6) , 1720-1725
- https://doi.org/10.1073/pnas.57.6.1720
Abstract
On the basis of DNA ribopolymer reactivities, differences in content of dC [deoxycytosine]-and dA [deoxyadenosine]-rich sequences were observed among DNA''s from nononcogenic, weakly oncogenic, and highly oncogenic adeno-viruses. SV40 [Simian vacuolating] virus DNA was also analyzed. The oncogenic adenovirus DNA''s contain fewer dC-rich sequences and more dA-rich sequences than DNA''s from the nononcogenic adeno-viruses. SV40 virus DNA contains relatively more dA-rich sequences than the highly oncogenic adenovirus DNA''s. There are few, if any, dC-rich sequences detectable in SV40 virus DNA. These findings may relate to viral oncogenicity.This publication has 18 references indexed in Scilit:
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