Preparation of some 2,3,5,6,7,8,8a‐heptahydrothiazolo[3,2‐a]‐s‐triazine‐5,7‐diones
- 1 March 1967
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 4 (1) , 93-95
- https://doi.org/10.1002/jhet.5570040116
Abstract
A number of 2‐substituted‐2‐thiazolines have been found to react readily with two moles of isocyanic acid in ethereal solution to give 2, 3, 5, 6, 7, 8, 8a‐heptahydrothiazolo‐[3,2‐a]‐s‐triazine‐5, 7‐diones (IIa‐e). Preliminary reports indicate some activity of these compounds against Walker's carcinosarcoma 256 in rats.Keywords
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