THE OXIDATION OF GLUCOSE BY PENICILLIUM CHRYSOGENUM

Abstract
Manometric data on the oxidation of glucose, D-glucose -1-C14 and D-glucose-2-C14 indicated that P. chrysogenum strain NRRL 1951-B25 metabolizes glucose by an oxidative pathway and that the first carbon to leave the molecule is from the 1-position. Uniformly labeled C14-giucose was converted to labeled glucose-6-phosphate and 6-phosphoglu-conate, indicating that the mechanism involves the phosphorylated compounds rather than the free acids.